Table 1.
Secondary cause | Number affected | % of total (n = 61)a |
---|---|---|
Idiopathic—no cause found | 24 | 39 |
History of amenorrhea > 6 months | 21 | 34 |
Anorexia nervosa | 10 | |
Depot medroxyprogesterone acetate | 2 | |
Medications to suppress pituitary function | 1 | |
Glucocorticoid exposure | 8 | 13 |
Rheumatologic disease | 3 | |
Organ transplant (liver, lung, kidney) | 3 | |
Celiac disease (based on serologic study) | 6 | 10 |
Medications to suppress pituitary function (<6 months) | 1 | 2 |
Hyperparathyroidism | 3 | 5 |
Seizure medication use | 2 | 3 |
Hyperthyroidism | 1 | 2 |
Hereditary exostosis | 1 | 2 |
Percent of total is >100%. Many women had more than one secondary cause (e.g., some women with celiac disease or glucocorticoid exposure also had amenorrhea).