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Cytochrome c levels in cytosolic and mitochondrial fractions of medullary interstitial cells (MICs) following exposure to 600 mosmol/L for 3, 6, 12 and 24 hours. Cytosolic cytochrome c abundance was markedly increased at 6 and 12 hours. Cytochrome c levels were determined using western blot; iso=isotonic medium (295 mosol/L), h= hours, HT=hypertonic culture medium. All values are mean ± SEM of n=4. *p<0.05 compared to isotonic control at 0 hours.
