Table 1.
Summary of subcellular localization, possible cellular functions and predicted associations with human diseases. Charcot-Marie-Tooth disease type 1C (CMT1C); Extramammary Paget disease (EMPD); Crohn's Disease (CD); Ulcerative colitis (UC); DiGeorge syndrome (DGS); Velo-cardio-facial syndrome (VCFS); conotruncal anomaly face syndrome (CTAF).
| NCBI accession # | Protein name | Size (aa) | Subcellular localization | Human diseases association | Putative cellular functions | References |
|---|---|---|---|---|---|---|
| NP_43186.1 | CYYR1 | 154 | Membrane (predicted) | Neuroendocrine tumors | Unknown | [32, 33] |
| NP_055528.1 | LAPTM4α | 233 | Intracytoplasmic membrane (predicted) | Unknown | Nucleosides and its derivatives transport (by similarity) | [31, 46, 47] |
| NP_004853.2 | LITAF | 161 | Intracytoplasmic membrane | CMT-1C; EMPD; CD/UC; B-cell lymphomas | Lysosomal sorting; tumor suppression;trans-cription regulation | [16, 26, 39, 40, 41, 42, 43, 43, 48, 49] |
| NP_064567.2 | PMEPA1 | 287 | Golgi-associated | Cancers | Cell growth inhibition | [24, 35, 36, 44, 50] |
| NP_005 975.1 | SLC25A1 | 311 | Mitochondria membranes (predicted) | DGS; VCFS; CTAF | Citrate-H+/malate exchange (by similarity) | [51, 52] |