Table 1.

Two-by-two contingency table

	within DPClus cluster	without DPClus cluster	total
KEGG pathway	a	b	a+b
non-KEGG pathway	c	d	c+d
totals	a+c	b+d	n

a is the number of metabolites in the KEGG pathway belonging to the DPClus cluster, a+b indicates the total number of metabolites in the KEGG pathway, a+c the number of metabolites in the DPClus cluster, and n the total number of metabolites in the profiling data. Rows reflect presence/absence within the KEGG pathway. Columns contain each of the 2 DPClus clusters. For each KEGG pathway the metabolites belonging to the 2 comparison groups are shown.