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. 2011 Jan 28;6(1):e14616. doi: 10.1371/journal.pone.0014616

Table 2. The differently expressed proteins identified based on two or more peptides in CD4+ T cells between active VKH patients and normal individuals.

Gene symbol Swiss-prot accession No. Identified proteins Expression Ratioa (VKH:NC) Xcorrb t-test p MH+ (Da) Mass stdev (Da) Identified Peptide
Up-regulated in VKH
VIM B0YJC4 Vimentin 2.8 2.42 0.00004 1060.7690 0.08313 159 R.QVDQLTNDK.A 169
5.53 0.00002 1169.9804 0.11453 129 K.ILLAELEQLK.G 140
2.27 0.00061 1428.8390 0.13478 50 R.SLYASSPGGVYATR.S 65
3.16 0.00031 1115.8539 0.14490 105 K.VELQELNDR.F 115
3.36 0.00032 1323.8875 0.13155 196 R.EEAENTLQSFR.Q 208
3.99 0.00045 1406.1375 0.30727 223 K.VESLQEEIAFLK.K 236
3.30 0.00030 1533.9759 0.26803 222 R.KVESLQEEIAFLK.K 236
3.30 0.00029 1312.8985 0.35813 207 R.QDVDNASLAR.L 218
2.26 0.00061 1226.9591 0.20369 294 K.FADLSEAANR.N 305
KRT10 P13645 Keratin, type I cytoskeletal 10 2.0 2.26 0.00449 993.8803 0.14940 237 K.YENEVALR.Q 246
2.49 0.00409 1435.8816 1.01701 439 K.IRLENEIQTYR.S 451
3.40 0.00108 2083.0051 0.17698 422 R.AETECQNTEYQQLLDIK.I 440
2.27 0.02983 1262.8610 0.14280 450 R.SLLEGEGSSGGGGR.G 465
3.03 0.00403 1031.5372 0.57250 257 R.VLDELTLTK.A 267
3.84 0.00012 1494.0186 0.19081 322 R.SQYEQLAEQNRK.D 335
2.26 0.00448 1236.916 0.16415 165 R.ALEESNYELEGK.I 178
ATP5B P06576 ATP synthase subunit beta, mitochondrial precursor 1.8 2.26 0.00433 1988.1477 0.17359 387 R.AIAELGIYPAVDPLDSTSR.I 407
3.57 0.00622 975.7282 0.15882 201 K.IGLFGGAGVGK.T 213
2.67 0.00022 1088.6165 0.50286 188 K.VVDLLAPYAK.G 199
ACTA2 P62736 Actin, aortic smooth muscle 1.8 3.83 0.01604 1354.8744 0.12513 52 K.DSYVGDEAQSKR.G 65
3.12 0.00290 1198.7264 0.08676 52 K.DSYVGDEAQSK.R 64
KRT2 P62736 Keratin, type II cytoskeletal 2 epidermal 1.8 4.91 0.00099 1191.8102 0.09092 374 K.YEELQVTVGR.H 385
4.89 0.00012 1461.0514 0.45310 302 K.VDLLNQEIEFLK.V 315
3.95 0.00025 1372.6575 0.48309 441 K.LNDLEEALQQAK.E 454
KRT1 P04264 Keratin, type II cytoskeletal 1 1.6 2.24 0.00899 993.8803 0.14940 443 K.LNDLEDALQQAK.E 456
4.70 0.00027 1435.8816 1.01701 343 R.SLDLDSIIAEVK.A 356
3.08 0.00072 2083.0051 0.17698 185 K.SLNNQFASFIDK.V 198
ALB A6NBZ8 Uncharacterized protein ALB 1.6 2.95 0.04948 1444.1611 0.54524 286 K.YICENQDSISSK.L 299
3.08 0.00704 1512.1173 0.04618 438 K.VPQVSTPTLVEVSR.N 453
2.95 0.04947 1078.9591 0.10821 499 K.CCTESLVNR.R 509
Down-regulated in VKH
SFRS1 Q07955 Isoform ASF-1 of Splicing factor, arginine/serine-rich 1 0.50 2.52 0.00007 1255.5932 0.37017 17 R.IYVGNLPPDIR.T 29
2.78 0.03060 1078.9591 0.10822 154 R.DGTGVVEFVR.K 165
3.37 0.00126 1417.7458 0.11825 142 R.EAGDVCYADVYR.D 155

a: average expression ratio;

b: cross-correlation score.