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. 2011 Jan 28;6(1):e14542. doi: 10.1371/journal.pone.0014542

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Mammi et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Sildenafil chronic treatment (1 µM/72 h) enhances eNOS phosphorylation in basal condition and after HG treatment, but not significantly after Gluc-N treatment. Full bars represent conditions without sildenafil, dashed bars represent sildenafil treatment. Ctrl was expressed as 100%. Means ± S.E. (n = 5). *p<0.05 vs Ctrl, ‡ p<0.05 vs insulin; † p<0.05 vs HG; †† p<0.05 vs HG + insulin.