Figure 4. The effect of CEppt on Aβ plaques formation in 5XFAD Alzheimer's disease model mice.

(A) Histological images of frontal cortex sections stained with Aβ antibody 6E10 from vehicle-treated 5XFAD mice, and (B) CEppt-treated 5XFAD mice. (C) Histological images of frontal cortex sections stained with Congo red from vehicle-treated 5XFAD mice, and (D) CEppt-treated 5XFAD mice. Scale bar = 100 µm. (E) Quantification of the % plaque load area of hippocampal sections from 5XFAD mice with or without CEppt treatment determined by 6E10 staining. (F) Quantification of the % plaque load area of hippocampal sections from 5XFAD mice with or without CEppt treatment determined by Congo red staining.