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. Author manuscript; available in PMC: 2012 Feb 11.
Published in final edited form as: J Mol Biol. 2010 Nov 25;406(1):75–91. doi: 10.1016/j.jmb.2010.11.031

Fig. 6.

Fig. 6

Comparison of caspase-6 and caspase-7 structures and CD spectra in the presence or absence of the active-site ligands VEID or DEVD. (a) CD spectra of caspase-6 bound to active-site ligand VEID (gray) or in the apo state with no ligand bound (black). (b) CD spectra of caspase-7 bound to active-site ligand DEVD (gray) or in the apo state with no ligand bound (black). (c) Comparision of [θ]208/[θ]222 for apo and substrate-bound states of caspase-6 and caspase-7. (d) Superposition of mature ligand-free caspase-6 ΔN D179CT (orange) with caspase-7 (1F1J, green) bound to the substrate-like ligand DEVD (purple dots).