Table 3.

Comparison of Predicted Change in Viral Load from Baseline

	Physician's selection		RDI system
	Initial	Final	Aa	Ba
A: All cases (n = 114)
Mean predicted change in viral load from baseline	−1.88	−1.90	−2.03	−2.03
Median	−1.85	−1.85	−1.98	−1.98
Proportion with > 2 log reduction	39%	41%	50%	50%
Statistical significance (vs physician's initial selection)b		p = 0.06	p < 0.0001	p < 0.0001
B: Cases where the treatment decision was changed (n  =  38)
Mean	−1.92	−1.99	−2.12	−2.13
Median	−1.91	−1.99	−2.06	−2.07
Proportion with > 2 log reduction	39%	50%	58%	58%
Statistical significance (vs. physician's initial selection)b		p < 0.05	p < 0.0001	p < 0.0001

^aA, Alternative regimens with no more drugs than the physician's initial selection; B, Alternative regimens with no more than six drugs.

^bOne tailed t tests.