Table 4.

Results of three-way analyses examining the impact of schizophrenia risk, a history of depression, and participant’s sex on cognitive performance.

General Cognitive Ability “g”	dferror	Schizophrenia Risk		Depression Hx		Sex		Schizophrenia Risk x Depression Hx		Schizophrenia Risk x Sex		Depression Hx x Sex		Schizophrenia Risk x Depression Hx x Sex
		F	p	F	p	F	p	F	p	F	p	F	p	F	p
	995	18.91	<.001	1.42	.233	2.47	.116	2.93	.087	4.48	.034	0.29	.591	8.55	.004
		Schizophrenia Risk		Depression Hx		Sex		Schizophrenia Risk x Depression Hx		Schizophrenia Risk x Sex		Depression Hx x Sex		Schizophrenia Risk x Depression Hx x Sex
	dferror	F	p	F	p	F	p	F	p	F	p	F	p	F	p
Processing Speed	1031	26.54	<.001	1.48	.224	1.54	.214	3.29	.070	3.94	.047	0.04	.846	3.27	.071
N-back Performance	857	16.18	<.001	0.16	.688	6.45	.011	0.24	.623	2.26	.133	0.50	.480	5.50	.019
Span Working Memory	893	0.03	.853	2.07	.150	6.79	.009	0.35	.557	0.22	.636	0.43	.513	0.64	.424
Verbal Memory	1031	3.34	.068	0.15	.695	3.65	.056	0.75	.386	1.94	.164	0.67	.412	1.41	.236
Visual Memory	756	1.59	.208	1.23	.268	0.26	.609	0.16	.685	0.40	.525	0.29	.590	0.17	.682
Card Sorting Ability	1002	10.63	.001	0.71	.399	0.69	.405	2.88	.090	5.43	.020	1.27	.260	9.76	.002

Hx, History, ANCOVA, analysis of covariance. All analyses completed with an ANCOVA controlling for age, education, and race differences among siblings and controls. Included in general cognitive ability “g” are the six cognitive domains listed above; “g” is a mean value of the performance in the six individual domains. All statistic values are F from the ANCOVA, adjusting for age, education, and race. Bold indicates significant findings (p < .05); italic indicates trends.