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. 2011 Jan;162(2):480–490. doi: 10.1111/j.1476-5381.2010.01061.x

Figure 6.

Figure 6

Effect of DISC0280 on hIL-15- and sIL-15Rα-induced increase in splenic NK1.1+ cells, CD3+ cells and spleen weight. C57BL/6/J male mice (n = 5 per group) were dosed once per day for 3 consecutive days with recombinant proteins as indicated. 24 h post treatment the spleens were weighed and cells extracted and (A) the number of NK1.1+ cells (B) CD3+ cells measured according to materials and methods and (C) weight of spleens reported as a ratio to body weight of animal. Error bars indicate SEM values. *P < 0.05, **P < 0.01, ***P < 0.001. hIL-15, human interleukin-15; hIL-15Rα, human interleukin 15 receptor α; PBS, phosphate-buffered saline; sIL-15Rα, soluble interleukin 15 receptor α.