Skip to main content
. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Cell Immunol. 2010 Nov 6;266(2):111–115. doi: 10.1016/j.cellimm.2010.10.009

Figure 4.

Figure 4

ROCK inhibition decreases the production of IL-17 and IL-21 in vivo. A. The frequency of CD4+ IL-17+ T cells from spleens and pancreatic lymph nodes (PLN) of NOD mice (n=3) or of NOD mice treated with Fasudil (n=3) was evaluated by intracellular FACS. *P≤0.001. B. Spleens from NOD mice (n=5) and NOD mice treated with Fasudil (n=5) were collected and IL-17 and IL-21 gene expression was analyzed by real-time RT-PCR. *P≤0.02 for IL-17 and *P≤0.0002 for IL-21.