Table 4.
Event rates (95% CI) for hospital admission and death due to thromboembolism* per 100 person years by CHADS2 score and by covariates
| Score and covariates | 1 year’s follow-up | 5 years’ follow-up | 10 years’ follow-up |
|---|---|---|---|
| CHADS2 score=0 | 1.67 (1.47 to 1.89) | 1.28 (1.19 to 1.38) | 1.24 (1.16 to 1.33) |
| CHADS2 score=1: | |||
| Heart failure | 2.80 (1.81 to 4.34) | 2.57 (2.00 to 3.30) | 2.31 (1.82 to 2.93) |
| Hypertension | 2.42 (2.04 to 2.87) | 1.95 (1.77 to 2.16) | 1.94 (1.77 to 2.13) |
| Age≥75 | 5.97 (5.55 to 6.41) | 4.77 (4.55 to 5.00) | 4.64 (4.44 to 4.85) |
| Diabetes mellitus | 3.00 (1.97 to 4.55) | 2.37 (1.84 to 3.05) | 2.42 (1.93 to 3.04) |
| CHADS2 score=2: | |||
| Diabetes + heart failure | 6.36 (3.31 to 12.23) | 6.36 (4.33 to 9.34) | 5.96 (4.12 to 8.63) |
| Diabetes + hypertension | 2.81 (1.80 to 4.41) | 2.75 (2.14 to 3.53) | 2.78 (2.21 to 3.50) |
| Diabetes + age≥75 | 7.83 (6.13 to 10.01) | 5.66 (4.75 to 6.74) | 5.37 (4.52 to 6.36) |
| Heart failure + hypertension | 4.44 (3.23 to 6.10) | 3.44 (2.80 to 4.22) | 3.28 (2.71 to 3.97) |
| Heart failure + age≥75 | 6.63 (5.77 to 7.62) | 5.56 (5.06 to 6.10) | 5.50 (5.03 to 6.02) |
| Hypertension + age≥75 | 6.93 (6.30 to 7.62) | 5.65 (5.31 to 6.01) | 5.47 (5.15 to 5.80) |
| Previous thromboembolism | 15.46 (13.41 to 17.83) | 8.25 (7.40 to 9.20) | 7.74 (6.98 to 8.57) |
*Includes peripheral artery embolism, ischaemic stroke, and pulmonary embolism.