Table 4.

Maximum concentrations of Tempol and 3-CP in various tissues

	3-CP				Tempol				Two Tailed T-test
Tissue	[3-CP]max	SEM	tmax	N	[Tpl]max	SEM	tmax	N	P([3-CP]max≠[Tempol]max)
Jugular Vein	6.6 mM	2 mM	0 s	8	8.1 mM	1.3 mM	0 s	7	P = 0.54
SCC	0.9 mM	0.1 mM	160 s	6	0.8 mM	0.1 mM	0 s	5	P = 0.50
HT-29	-	-	-	-	0.6 mM	0.1 mM	20 s	4	-
KHT	-	-	-	-	0.6 mM	0.1 mM	40 s	4	-
Leg muscle (tumor side)	0.8 mM	0.1 mM	280 s	6	0.6 mM	0.1 mM	60 s	5	P = 0.20
Leg muscle (contra to tumor)	0.9 mM	0.1 mM	280 s	5	0.5 mM	0.1 mM	80 s	6	P = 0.02
Ant. leg muscle	0.9 mM	0.2 mM	220 s	5	1.1 mM	0.2 mM	40 s	6	P = 0.50
Brain	0.5 mM	0.1 mM	20 s	5	1.4 mM	0.2 mM	20 s	4	P = 0.02
Lacrimal glands	4.9 mM	0.5 mM	20 s	4	5.6 mM	0.8 mM	20 s	3	P = 0.51
Salivary Gland	1.4 mM	0.1 mM	60 s	7	2.0 mM	0.5 mM	20 s	5	P = 0.30
Rectum	3.1 mM	0.2 mM	40 s	5	3.7 mM	1 mM	20 s	5	P = 0.59
Root of Tongue	1.2 mM	0.4 mM	120 s	5	3.0 mM	0.6 mM	20 s	5	P = 0.05
Kidney (Left)	7.1 mM	0.5 mM	20 s	6	4.5 mM	0.7 mM	20 s	5	P = 0.02
Kidney (Right)	7.2 mM	0.5 mM	20 s	6	6.1 mM	0.8 mM	20 s	5	P = 0.29
Liver	4.7 mM	0.3 mM	20 s	6	1.6 mM	0.2 mM	20 s	6	P < 0.01

Significant P values are bold.