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. Author manuscript; available in PMC: 2011 Dec 22.
Published in final edited form as: J Am Chem Soc. 2010 Nov 24;132(50):17751–17759. doi: 10.1021/ja104496q

Figure 2.

Figure 2

Dependence β-deuterium secondary isotope effects on substrate concentration for DmAChE-catalyzed hydrolysis of ATCh. Reaction conditions and data acquisition are described in the Experimental section. The parameters of the least-squares fit to equation 2 (see text) are D3Vmax = 1.12 ± 0.01, D3Km = 1.18 ± 0.04, and D3β= 0.87 ± 0.03.