Table 2.
Investigator characteristics and clinical trial experience
Characteristics | Respondents (N = 732) |
---|---|
n (%) | |
Primary appointment | |
University or academic teaching hospital | 684(93) |
Non-academic community-based hospital | 27(4) |
Other (e.g. private practice, cancer centre, pharmaceutical) | 21(3) |
Type of clinical trial | |
Non-industry trials only | 240(33) |
Industry trials only | 54(7) |
Both non-industry and industry trials | 406(55) |
None | 28(4) |
Did not answer | 4(1) |
Number of years of experience in clinical trials | |
≤ 5 | 192(26) |
> 5 | 489(67) |
Not applicable | 28(4) |
Did not answer | 23(3) |
Most senior role in clinical trial | |
Principal investigator for entire trial -(trial PI) | 466(64) |
Principal investigator for site, No overall PI experience- (site PI) | 177(24) |
Other (No PI or site-PI experience) | 56(8) |
Did not answer | 33(5) |
Intervention(s) studied * | |
Drug therapy | 552(75) |
Device/equipment | 217(30) |
Diagnostic tests | 174(24) |
Surgery/procedure | 151(21) |
Education/counselling | 139(19) |
Management policy (e.g. specific thresholds for transfusion) | 89(12) |
Complementary and alternative medicine | 78(11) |
Psychotherapy | 37(5) |
Other (e.g. exercise, nutrition, radiation) | 113(15) |
Trial sites | |
Single | 94(13) |
Multiple | 252(34) |
Both (single and multiple) | 353(48) |
Did not answer | 33(5) |
Conflict of interest exposure | |
Any | 269(37) |
Personal only | 33(5) |
Witness of colleague | 184(25) |
Both personal and witness of colleague | 52(7) |
None | 402(55) |
Did not answer | 61(8) |
Note:
* The sum of response options is greater than 100% because survey respondents may have investigated more than one intervention type in different trials.