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Effect of simvastatin on the expression of hepatic genes which play roles in cholesterol transport. A, Effect of simvastatin on the mRNA expression of hepatic genes by real-time PCR. Expression levels of mRNA are indicated as fold differences compared with model mice. B, Effect of simvastatin on the protein expression of hepatic genes by western blots. C, Densitometric quantitation of western blot data (n = 5) by Quantity One software. * P < 0.05, ** P < 0.01 versus model group.
