Table 2.
Effect of Simvastatin on plasma lipoprotein lipids and apoA-I concentrations in apoE-/- mice
Model (apoE-/-) | Simvastatin (5 mg/kg) | |
---|---|---|
Animal number (n) | 11 | 10 |
TC(mmol/L) | 24.69 ± 5.34 | 22.07 ± 4.12 |
TG(mmol/L) | 1.13 ± 0.37 | 1.24 ± 0.47 |
Non-HDL-C (mmol/L) | 22.06 ± 4.87 | 18.93 ± 3.89 |
HDL-C (mmol/L) | 2.63 ± 0.35 | 3.14 ± 0.34** |
apo-AI(mg/dl) | 4.24 ± 1.01 | 11.58 ± 2.03** |
Values are the means ± SD. *compared with model, p < 0.05. **compared with model, p < 0.01