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cAMP formation in Gi2α(+/G184S) platelets. (A) Effect of ADP on cAMP levels after stimulation with forskolin (left) or PGI2 (right). (B) Percent inhibition of cAMP levels with increasing dosages of ADP after stimulation with forskolin (left) and PGI2 (right). Mean ± SEM. The data shown represent averaged measurements from 4 (forskolin) or 3 (PGI2) experiments. One mouse of each genotype was used in each experiment.
