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. 2010 Sep 17;116(25):5615–5621. doi: 10.1182/blood-2010-03-274506

Figure 2.

Figure 2

Development γδ T-cell lymphoma in Id3−/− mice. (A-B) Flow cytometric analysis of the lymphomatous cells in a representative Id3−/− mouse (mouse no. 44). The lymphomatous cells are γδTCR+CD3+, but αβTCR− (A, R1); The gated R2 area represents the non-γδ T cells. γδ T-cell lymphoma cells (R1) were seen in the lymph nodes (LN), thymus (thy), bone marrow (BM), and liver (liv) of Id3−/− mice (B). (C) The survival curve of Id3−/− mice. Control mice (Id3+/+ and +/−, n = 50 mice); Id3−/− mice with lymphoma (−/− lymphoma, n = 38 mice); Id3−/− mice without lymphoma (−/− not lymphoma, n = 104 mice). ** P < .01.