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. 2011 Jan 31;6(1):e16197. doi: 10.1371/journal.pone.0016197

Figure 6. Expression of the ABD of βI-spectrin increases the size of the PSD.

Figure 6

A, Merged images from CA1 pyramidal neurons in hippocampal slice cultures co-transfected with PSD-95 fused to GFP (green) and mCherry (red), with or without an unlabelled βI-spectrin ABD construct. The areas of the clusters of PSD-95 in the heads of spines expressing the ABD of βI-spectrin were larger than in cells expressing PSD-95 alone. Scale bar = 4 µm (left), 1 µm (right). B, Cumulative probability plot showing that the area of the PSD was significantly larger in spines expressing PSD-95-GFP together with the ABD of βI-spectrin than in spines expressing PSD-95-GFP alone (n = 400 spines/4 neurons/condition; p<0.05, K-S test).