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. 2011 Jan 31;6(1):e16414. doi: 10.1371/journal.pone.0016414

Figure 7. Rosette disruption assays with ITvar9 antisera against six P. falciparum rosetting laboratory strains.

Figure 7

Antisera raised to ITvar9 domains, and paired pre-immune sera, were used at 1/20 dilution in rosette disruption assays with R29, PAR+, Muz12, HB3R+, TM284 and TM180. Antisera were as follows: A) NTS-DBL1α, B) DBL1α, C) NTS-DBL1α-CIDR1γ, D) DBL2γ, E) DBL3ε, F) DBL4δ and G) CIDR2β. Disruption of rosetting was only seen with R29 parasites. Data shown are the mean and standard deviation from three independent experiments. The control (with binding medium only added) had more than 50% of infected erythrocytes in rosettes.