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. 2011 Jan 31;6(1):e16551. doi: 10.1371/journal.pone.0016551

Table 4. Mean evolutionary rate estimates (x10−3) and 95%HPD for whole E1/E2 sequences and separate codon positions (1st +2nd and 3rd) and root tMRCAs (in months before the last sample) and months of follow-up in 8 patients and 2 controls.

Patient M.E.R. (95%HPD) R.E.R.1st+2nd (95%HPD) R.E.R. 3rd (95%HPD) R.tMRCA (95%HPD) Months
# 1 1.9 (1.1–2.9) 0.9 (0.7–1.2) 1.1 (0.6–1.6) 36.9 (36–38) 36
# 2 0.6 (0.2–1.1) 0.9 (0.6–1.2) 1.2 (0.6–1.8) 37.2 (27–53) 26
# 3 2.0 (0.4–3.4) 1 (0.7–1.3) 1.0 (0.5–1.5) 33.3 (20–70) 24
# 4 1.0 (0.5–1.6) 0.8 (0.5–1.1) 1.4 (0.9–2.0) 43.7 (39–50) 39
# 5 2.1 (1.3–2.9) 1.1 (0.8–1.3) 0.9 (0.5–1.3) 33.6 (33–34) 33
# 6 2.8 (1.7–4.2) 1 (0.8–1.2) 0.99 (0.6–1.4) 22.9 (21–25) 20
# 7 0.17 (0.03–0.3) 1.1 (0.7–1.3) 0.9 (0.3–1.5) 78.0 (35–144) 30
# 8 2.3 (0.9–3.7) 1.2 (0.9–1.5) 0.6 (0.1–1.6) 14.5 (14–15) 14
# 9 0.37 (0.15–0.6) 0.4 (0.2–0.6) 2.2 (1.8–2.6) 76.8 (52–119) 48
# 10 0.22 (0.06–0.4) 0.9 (0.6–1.1) 1.3 (0.7–1.9) 295.9 (137–525) 82

Group A: Subjects #1-5; group B: Subjects #6-8; group C (controls): Subjects #9 and 10.

E.R. = Evolutionary rate estimates in substitution/site/year.

R.tMRCA =  Tree root time (months before the most recent sample).

M.E.R. =  Mean evolutionary rate.

R.E.R. = Relative evolutionary rate.