Table 5. Significance level (p value) of the positive selection versus neutral model comparison by two different methods (NY, REL see methods section for details) and sites under positive or negative selection.
| Patient | NY | REL | Positive selection | Negative selection |
| # 1 | <0.001 | <0.001 | 401, 405 | 341, 378* |
| # 2 | ns | ns | - | - |
| # 3 | ns | 0.002 | 372, 384, 397, 399, 401 | 340, 344, 354*, 370, 411 |
| # 4 | 0.1 | 0.04 | 417* | - |
| # 5 | <0.001 | <0.001 | 365, 384*, 392, 396, 397*, 400, 403, 410 | 346*, 359*, 383 |
| # 6 | <0.01 | 0.001 | 349, 384, 386, 396*, 397, 398, 399*, 401, 408, 410 | 339*, 355*, 363*, 365 |
| # 7 | ns | ns | - | 398 |
| # 8 | ns | ns | - | 409* |
| # 9 | ns | ns | - | 339*, 341, 361, 384, 394, 399*, 403 |
| # 10 | ns | 0.02 | - | 342*, 355*, 361*, 378*, 397* |
n.s. = not significant (p>0.1).
* = indicates sites under significant selection at internal branches.