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. 2011 Jan 31;6(1):e16598. doi: 10.1371/journal.pone.0016598

Figure 9. USP7 NTD and CTD both regulate PML I and IV NBs.

Figure 9

(A) CNE2 cells expressing the indicated individual PML isoforms were transfected with plasmids expressing myc-tagged USP7 NTD or CTD, then were fixed and stained for myc and PML and counter stained with DAPI. (B) The number of PML NBs per cell were counted for 100 cells that were expressing or were not expressing (control) the USP7 domain for samples in (A). Average numbers are shown with standard deviations (from 3 independent experiments).