Table 2. SMI-049 specific SNPs resulting in premature stop codons.
Reference position (H37Rv) | Reference | Allele variations | Overlapping annotations | Amino acid change |
218204 | C | T | Gene: Rv0186 bglS, beta-glucosidase | R646 Stp (691 aa) |
281238 | C | T | Gene: Rv0235c, probable transmembrane protein | W459 Stp (482 aa) |
2129419 | G | T | Gene: Rv1879, hypothetical protein | E15 Stp (378 aa) |
2374245 | C | T | Gene: Rv2114, hypothetical protein | Q138 Stp (207 aa) |
3689523 | G | T | Gene: Rv3303 lpdA, Lipoamide dehydrogenase | C472 Stp (493aa) |
4351039 | G | T | Gene: Rv3872 PE35 | E99 Stp (99aa) |