Table 5. Mean IFNγ response to M.tb PPD by vitamin D status, controlling for season of blood collection at 3 and 12 months post BCG, among vaccines.
No. of infants | Mean IFNγ to M.tb PPD (pg/ml) | Mean difference in IFNγ to M.tb PPD between infants with low and high vitamin D (95% CI) | P value | ||
3 months post BCG | Hypovitaminosis (<30 ng/ml) | 20 | 2426 | 829 (84, 1575) * | 0.030 |
Sufficient Vitamin D (>30 ng/ml) | 27 | 1597 | |||
Adjusted for season of blood collection | 883 (83, 1683) ** | 0.031 | |||
12 months post BCG | Vitamin D deficiency (<20 ng/ml) | 18 | 1542 | 466 (−352, 1283) * | 0.255 |
Vitamin D (>20 ng/ml) | 19 | 1076 | |||
Adjusted for season of blood collection | 523 (−375,1420) ** | 0.244 |
*unadjusted (“crude”),
**adjusted.