Table 3.

Unadjusted and Multivariate Relative Risk Regression Results for oxLDL-IC association with High CAC status.

Relative risks associated with risk factors of CAC	Model 1 (Unadjusted)	Model 2	Model 3	Model 4*
oxLDL-IC (1 SD Increase)	1.51 (1.20–1.88) §	1.36 (1.12–1.67) §	1.35 (1.10–1.65) §	1.26 (1.03–1.54) †
Baseline LN AER		1.17 (0.89–1.54)	1.07 (0.83–1.37)	1.03 (0.80–1.33)
Experimental Treatment Group		0.95 (0.61–1.47)	0.97 (0.63–1.48)	0.98 (0.64–1.52)
Secondary Retinopathy Cohort		0.85 (0.45–1.61)	0.88 (0.47–1.65)	0.82 (0.43–1.56)
HbA1C (1 unit increase, %)		1.08 (0.93–1.25)	1.07 (0.91–1.24)	1.05 (0.91–1.21)
Diabetes Duration at BL (1 yr increase)		1.07 (1.01–1.15) †	1.07 (1.01–1.14)†	1.08 (1.01–1.15)†
Age at BL (1 year increase)		1.12 (1.08–1.16) §	1.11 (1.06–1.15) §	1.09 (1.05–1.14) §
Male (men versus women)		1.92 (1.20–3.09) §	1.68 (1.02–2.78) †	1.70 (1.04–2.76) §
SBP (10 unit increase, mmHg)			1.18 (0.98–1.42)	1.20 (0.99–1.44)
Baseline Smoking (yes vs. no)			1.71 (1.11–2.64) †	1.56 (1.01–2.41) †
LDL (1 SD increase)				1.41 (1.17–1.70) §

Risk Models:

1: Ox LDL IC only

2: Adjusted for DCCT Treatment Group, Retinopathy Cohort, age, gender, baseline HbA1C %, CT Scanning location, Baseline AER, and Baseline Diabetes Duration.

3: Additionally Adjusted for Smoking Status and Systolic Blood Pressure

4: Additionally adjusted for baseline LDL

^†p < 0.05

^§p < 0.01

^*LDL was chosen for model inclusion based on significance within the model. HDL, Cholesterol, Triglycerides, and BMI were highly non-significant when included in the model, and were therefore removed from model 4.