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. Author manuscript; available in PMC: 2012 Jan 28.
Published in final edited form as: Biochem Biophys Res Commun. 2010 Dec 25;404(4):979–984. doi: 10.1016/j.bbrc.2010.12.095

Fig. 1.

Fig. 1

NHERF2 but not NHERF1 augmented the enhancing effect of WNK4 on TRPV5. A. NHERF1 exhibited no effects on TRPV5-mediated Ca2+ uptake in the presence and absence of WNK4 (n = 21). B. NHERF2 increased TRPV5-mediated Ca2+ uptake and significantly augmented the enhancing effects of WNK4 on TRPV5 (n = 56). C. A representative Western blot analysis using antibody against TRPV5. D. Immunofluorecent staining of TRPV5 in sections of oocytes expressing TRPV5, TRPV5 and WNK4, TRPV5 and NHERF2, and TRPV5, NHERF2 and WNK4, respectively. Bar, 25 μm. * indicates P < 0.05 compared to TRPV5 alone group. NS, not statistically significant (P > 0.05).