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(A) Relationship between ALC and B-cell count in 818 patients who met the 1988 and 1996 IWCLL-NCI diagnostic CLL criteria (4) (i.e. ALC of at least 5.0×109/L and immunologically confirmed diagnosis of CLL by flow cytometry). (B) Relationship between ALC and B-cell count in 124 patients who would be reclassified as MBL using the 2008 CLL diagnostic criteria.7
