Table 3.

Activation to Threat (> Non-threat) between placebo and alcohol sessions

			Volume (mm3)	Z-score		MNI Coordinates
Session	Brain Region	Laterality			p-value	x	y	Z
PBO	Supplementary Motor Area	R	1184	3.82	<0.001	14	-12	52
		R	72	2.75	0.003	18	-30	52
	Middle Temporal Gyrus	R	1440	3.28	0.001	48	-50	6
	Cerebellum	L	280	3.14	0.001	-4	-68	-14
	Amygdala	R	176	2.91	0.002	22	8	-26
ALC	Inferior Frontal Gyrus	R	176	3.65	<0.001	48	46	-16
		R	1608	3.50	<0.001	48	40	-2
		L	328	3.34	<0.001	-52	44	-14
		L	568	2.92	0.002	-32	30	10
		L	424	2.79	0.003	-44	42	6
		R	232	2.79	0.003	44	20	22
		L	40	2.62	0.004	-52	22	26
	Middle Frontal Gyrus	L	728	3.61	<0.001	-40	46	32
		R	96	3.03	0.001	54	40	28
	Cerebellum	R	240	3.36	<0.001	42	-44	-30
	Inferior Parietal Gyrus	L	264	2.67	0.004	-34	-50	44
PBO > ALC	Mid Cingulate	L	488	3.94	<0.001	-6	-14	28
		R	48	2.64	0.004	10	6	36
	Thalamus	L	56	3.17	0.001	-8	-14	0
	Pallidum	L	56	2.89	0.002	-16	4	-6
	Amygdala	L	88	2.86	0.002	-12	2	-26
		R	32	2.63	0.004	14	-4	-26
	Putamen	L	88	2.84	0.002	-22	-2	-8
	Cerebellum	R	160	2.83	0.002	2	-62	-8
	Cuneus	R	64	2.77	0.003	2	-94	22
ALC > PBO	Inferior Parietal Gyrus	L	10416	4.06	<0.001	-36	-74	44
	Angular Gyrus	R	1520	3.99	<0.001	40	-64	54
	Inferior Frontal Gyrus	L	4984	3.93	<0.001	-50	42	-14
		R	296	3.21	0.001	48	46	-16
		L	456	2.95	0.002	-42	24	6
		L	248	2.76	0.003	-42	34	-2
		L	64	2.62	0.004	-44	38	8
	Superior Parietal Gyrus	R	128	3.28	0.001	24	-72	56
	Middle Frontal Gyrus	L	1728	3.24	0.001	-40	36	28
		R	144	3.04	0.001	58	44	12
	Superior Frontal Gyrus	L	504	3.18	0.001	-24	56	22
	Middle Occipital Gyrus	L	232	3.14	0.001	-42	-84	24
		R	88	2.85	0.002	34	-88	34
	Superior Occipital Gyrus	R	48	2.78	0.003	22	-74	46
	Inferior Temporal Gyrus	R	80	2.75	0.003	64	-52	-18

All activations are p < 0.005 (uncorrected); assessment of cluster volume was performed at p < 0.005 (uncorrected). ALC, alcohol; PBO, placebo; MNI, Montreal Neurologic Institute.