Table 4.
Activation to Face (> Shapes) between placebo and alcohol sessions
| Volume (mm3) | Z-score | MNI Coordinates | ||||||
|---|---|---|---|---|---|---|---|---|
| Session | Brain Region | Laterality | p-value | x | y | z | ||
| PBO > ALC | Fusiform Gyrus / Lingual / Calcarine Gyrus | R/L | 46632 | 4.36 | <0.001 | -36 | -62 | -14 |
| L | 608 | 3.04 | 0.001 | -30 | -4 | -38 | ||
| R | 56 | 2.73 | 0.003 | 28 | -4 | -42 | ||
| R | 88 | 2.72 | 0.003 | 40 | -44 | -20 | ||
| Subgenual Anterior Cingulate | R | 128 | 3.81 | <0.001 | 4 | 18 | -8 | |
| Mid Cingulate | R | 728 | 3.51 | <0.002 | 20 | -20 | 44 | |
| Superior Parietal Gyrus | L | 272 | 3.22 | 0.001 | -26 | -52 | 56 | |
| Cerebellum | R | 184 | 3.20 | 0.001 | 34 | -42 | -34 | |
| R | 208 | 3.14 | 0.001 | 50 | -58 | -34 | ||
| Cuneus | R | 1504 | 3.12 | 0.001 | 8 | -90 | 36 | |
| Amygdala | R | 80 | 3.04 | 0.001 | 14 | -4 | -22 | |
| Pallidum | L | 152 | 2.99 | 0.001 | -20 | 0 | -6 | |
| R | 40 | 2.81 | 0.002 | 20 | 0 | 0 | ||
| Mid Occipital Gyrus | R | 240 | 2.85 | 0.002 | 46 | -82 | 0 | |
| Precentral Gyrus | R | 144 | 2.83 | 0.002 | 56 | 4 | 50 | |
| L | 752 | 2.74 | 0.003 | -46 | -6 | 42 | ||
| Lingual Gyrus | R | 48 | 2.76 | 0.003 | 18 | -50 | -2 | |
| | ||||||||
| ALC > PBO | Inferior Temporal Gyrus | L | 280 | 3.38 | <0.001 | -56 | -58 | -6 |
| Superior Frontal Gyrus | R | 184 | 3.35 | <0.001 | 16 | 26 | 62 | |
| L | 760 | 3.26 | 0.001 | -24 | 64 | 16 | ||
| L | 288 | 3.08 | 0.001 | -8 | 42 | 32 | ||
| Mid Temporal Gyrus | R | 56 | 3.01 | 0.001 | 64 | -2 | -24 | |
| Superior Temporal Gyrus | R | 56 | 2.86 | 0.002 | 58 | -6 | -12 | |
| Mid Occipital Gyrus | L | 56 | 2.79 | 0.003 | -34 | -84 | 18 | |
All activations are p < 0.005 (uncorrected); assessment of cluster volume was performed at p < 0.005 (uncorrected). ALC, alcohol; PBO, placebo; MNI, Montreal Neurologic Institute.