. Author manuscript; available in PMC: 2012 Mar 15.

Published in final edited form as: Anal Biochem. 2010 Dec 10;410(2):206–213. doi: 10.1016/j.ab.2010.12.005

Table 2.

Kinetic constants for the cleavage of different ADAMTS13 substrates

Substrates	K_M	k_cat (min⁻¹)	Reference
XS-VWF	4.6 ± 0.8μM	44.8 ± 4.3	(this paper)
S-VWF	1.8 ± 0.2μM	17.7 ± 0.5	(this paper)
FRETS-VWF73^*	3.2 ± 1.1μM	58	[39]
VWF115^**	1.6 ± 0.5μM	8.4 ± 3.6	[40]
Multimeric VWF	15nM	0.83	[39]

Substrate similar to XS-VWF;

^**

Substrate similar to S-VWF