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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Biochem Pharmacol. 2010 Dec 22;81(5):649–660. doi: 10.1016/j.bcp.2010.12.014

Figure 4. Effect of Soraphen A on linoleate metabolism.

Figure 4

A. Pathway for linoleate metabolism [42, 62]. B. HepG2 cells were treated with soraphen A (100 nM) for 2 hrs before adding 14C-18:2,n-6 (50 µM). Six hours later cells were harvested for total lipid extraction, saponification, and RP-HPLC analysis. Results are reported at % Distribution of 14C in 18:2,n-6 products; mean ± SD, n=3, t-test.