HepG2 cells were infected Ad-Luc or Ad-FADS1 + Ad-FADS2 and treated with DMSO or soraphen A (100 nM) and 50 µM 14C-linoleate as described in Figs. 6. The media was collected at the time of cell harvest and assayed for fatty acid oxidation products, ASM, acid soluble material (Methods). Results are reported as ASM, nmoles/mg protein, mean ± SD, n=4; *. p≤0.05 DMSO versus soraphen A; #, Ad-Luc versus Ad-FADS1 + Ad-FADS2, Anova-one way.