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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Biochem Pharmacol. 2010 Dec 22;81(5):649–660. doi: 10.1016/j.bcp.2010.12.014

Figure 9. Effect of enhanced PUFA synthesis on FAO in HepG2 cells.

Figure 9

HepG2 cells were infected Ad-Luc or Ad-FADS1 + Ad-FADS2 and treated with DMSO or soraphen A (100 nM) and 50 µM 14C-linoleate as described in Figs. 6. The media was collected at the time of cell harvest and assayed for fatty acid oxidation products, ASM, acid soluble material (Methods). Results are reported as ASM, nmoles/mg protein, mean ± SD, n=4; *. p≤0.05 DMSO versus soraphen A; #, Ad-Luc versus Ad-FADS1 + Ad-FADS2, Anova-one way.