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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Pharmacol Res. 2010 Nov 18;63(2):146–150. doi: 10.1016/j.phrs.2010.11.003

Fig. 2. A suggested model for CMT-3 induced tumor cell cytotoxicity.

Fig. 2

CMT-3 induced cytotoxicity is due to both cell cycle arrest at G1/S interphase and free-radical induced-mitochondrial permeability changes and caspase activation. Both, cytosolic and ER mediated caspase activation.