Table 1.

NMR Assignments for EGM-556 (1) in DMSO-d₆

structural unit	position	13Ca δ, typeb	1H δ (m, J(Hz), int)c
Val-1	CO	168.7, qC
	α	58.2, CH	4.24 (dd, 9.6, 6.0, 1H)
	β	28.5, CH	2.25 (ds, 6.0, 6.6, 1H )
	β-CH3	18.9, CH3	0.89 (d, 6.6, 3H)
	β-CH3	19.3, CH3	0.89 (d, 6.6, 3H)
	NH		7.60 (d, 9.6, 1H)
Ile-2	CO	170.4, qC
	α	57.2, CH	4.26 (d, 9.6, 1H)
	β	35.6, CH	2.05 (m, 1H)
	γ	23.6, CH2	1.26 (m, 2H)
	β-CH3	15.5, CH3	0.81 (d, 6.6, 3H)
	γ-CH3	11.9 CH3	0.81 (t, 7.5, 3H)
	NH		8.10 (d, 9.6, 1H)
Ala-3	CO	173.0, qC
	α	48.8, CH	4.32 (dq, 6.3, 6.4, 1H)
	α-CH3	16.3, CH3	1.18 (d, 7.2, 3H)
	NH		8.56 (d, 6.3, 1H)
Val-4	CO	172.3, qC
	α	57.5, CH	4.14 (dd, 8.7, 7.2, 1H)
	β	29.8, CH	1.96 (ds, 6.9, 6.8, 1H)
	β-CH3	19.6, CH3	0.89 (d, 6.6, 3H)
	β-CH3	18.2, CH3	0.89 (d, 6.6, 3H)
	NH		7.74 (d, 8.7, 1H)
Hyppa-5	1	168.7, qC
	2	40.1, CH2*	2.42 (dd. 14.4, 1.8, 1H)
			2.88 (dd, 14.4, 10.5, 1H)
	3	72.9, CH	5.50 (ddd, 10.5, 7.1, 1.8, 1H)
	4	126.7, CH	6.28 (dd, 15.9, 7.1, 1H)
	5	132.4, CH	6.68 (d, 15.9, 1H)
	6	135.7, qC
	7	126.5, CH	7.44 (d, 7.2, 2H)
	8	128.7, CH	7.36 (dd, 7.5, 7.2, 2H)
	9	128.1, CH	7.28 (t, 7.5, 1H)

^aMeasured at 150 MHz.

^bCarbon type established from ¹³C DEPT and/or gHMQC experiments.

^cMeasured at 600 MHz.

^*Overlapping with DMSO-d₆