Table 2.

CDR of rac-1 and Negishi arylation or vinylation

entry	electrophile	product	yield (%)	er (R:S)
1a			63	92:8
2a,b			59	6:94
3a			75	97:3
4a			69	95:5
5a			64	92:8
6a			60	91:9
7a,c			66	90:10
8a			60	93:7
9e			67	97:3
10d			46	88:12
11b,d			51	10:90
12d			50	93:7
13d			53	85:15
14a			63	92:8
15a,e			66	93:7

^a)stirred at rt for 18 h during step (iv),

^b)CDR using (S,R)-2;

^c)the aryl bromide contained a small amount of 2-bromobenzonitrile leading to formation of the ortho cyano constitutional isomer in 90:10 er;

^d)stirred at 60 °C for 22 h during step (iv),

^e)a small amount of the Z-alkene was obtained as a minor isomer in 92:8 er.