Table 3.
ROI | 13 weeks | 24 weeks | 40 weeks | 56 weeks |
---|---|---|---|---|
Total | ||||
Hippocampus | ||||
PSAPP | 72 ± 10 (N = 6) |
74 ± 10 (N = 5) |
91 ± 15 (N = 6) |
80 ± 13 (N = 5) |
CNT | 76 ± 14 (N = 6) |
87 ± 23 (N = 6) |
70 ± 16 (N = 7) |
78 ± 12 (N = 7) |
Dendritic Layer | ||||
PSAPP | 76 ± 10 | 76 ± 11 | 95 ± 16 | 82 ± 14 |
CNT | 77 ± 14 | 88 ± 23 | 71 ± 16 | 79 ± 13 |
PCL | ||||
PSAPP | 56 ± 7 | 62 ± 12 | 68 ± 9 | 66 ± 11 |
CNT | 66 ± 14 | 77 ± 24 | 52 ± 13 | 58 ± 9 |
CA3 | ||||
PSAPP | 58 ± 9 | 66 ± 6 | 77 ± 11 | 71 ± 6 |
CNT | 70 ± 18 | 81 ± 22 | 66 ± 17 | 75 ± 13 |
Hilus | ||||
PSAPP | 66 ± 10 | 72 ± 9 | 81 ± 12 | 78 ± 12 |
CNT | 75 ± 12 | 89 ± 21 | 81 ± 25 | 101 ± 32 |
Cortex | ||||
PSAPP | 100 ± 10 | 70 ± 20 | 90 ± 10 | 100 ± 20 |
CNT | 110 ± 10 | 110 ± 20 | 100 ± 20 | 100 ± 10 |
significantly different from 13 weeks
significantly different from 24 weeks
significantly different from CNT