. Author manuscript; available in PMC: 2011 Feb 1.

Published in final edited form as: J Mol Cell Cardiol. 2006 Dec 8;42(2):453–458. doi: 10.1016/j.yjmcc.2006.10.015

Table 1.

Hemodynamics during ischemia/reperfusion.

Group	Baseline	30-min Isch	180-min Rep

Control (group I)

HR	182 ± 6	172 ± 9	155 ± 8
MAP	86 ± 9	78 ± 8	71 ± 8
RPP	20,924 ± 2348	17,168 ± 2425	14,020 ± 2253

Sildenafil (groupII)

HR	198 ± 9	187 ± 8	161 ± 9^a
MAP	82 ± 10	66 ± 4	63 ± 5
RPP	19,408 ± 1439	14,960 ± 2764	13,236 ± 3112

Sildenafil+5-HD (group III)

HR	191 ± 8	186 ± 7	159 ± 14
MAP	84 ± 7	72 ± 6	67 ± 2
RPP	18,996 ± 1180	16,182 ± 1350	13,720 ± 1053^a

Vardenafil (group IV)

HR	188 ± 7	179 ± 12	146 ± 10^a,^b
MAP	89 ± 4	71 ± 3^a	60 ± 3^a,^b
RPP	19,740 ± 1563	15,380 ± 2170	10,804 ± 1235^a

Vardeafnil+5-HD (group V)

HR	181 ± 6	185 ± 8	160 ± 9
MAP	79 ± 4	74 ± 5	63 ± 7
RPP	17,652 ± 2080	16,650 ± 1460	12,320 ± 1833

5-HD (group VI)

HR	190 ± 11	185 ± 8	160 ± 7
MAP	75 ± 6	67 ± 5	61 ± 3
RPP	17900 ± 1142	14,215 ± 2055	11,840 ± 1788

Nitroglycerin (group VII)

HR	178 ± 16	185 ± 8	160 ± 7
MAP	85 ± 5	77 ± 5	72 ± 7
RPP	18,154 ± 1912	16,617 ± 1462	13,360 ± 1743

Values are Means±SEM. HR – Heart rate (beats/min); MAP – Mean arterial blood pressure (mmHg); RPP – Rate pressure product (mmHg/min),

P < 0.05 vs. Baseline;

P < 0.05 vs. 30 min. Ischemia.