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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Nat Rev Genet. 2010 Dec 30;12(2):87–98. doi: 10.1038/nrg2934

Figure 2. Use of RNA-seq for BCR–ABL fusion gene detection.

Figure 2

a | Breakpoint cluster region (BCR) and ABL1 gene transcripts. b | BCR–ABL fusion gene transcript. c | Sequence reads mapping across the BCR–ABL fusion gene site demonstrating the ability to accurately identify the site of gene fusion. The data were derived from RNA-seq analysis25 of the K562 transcriptome using the HeliScope (the raw data files are available at the University of California Santa Cruz Genome Browser and the Helicos Technology Center).