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. 2010 Nov 9;104(2):376–386. doi: 10.1038/sj.bjc.6605990

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Copyright © 2011 Cancer Research UK

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Effects of LY6K knockdown on cell growth. (A) LY6K mRNA expressions were markedly repressed in si-LY6K transfectants (BOY and KK47) in comparison with si-control transfectants. (B) Cell viability as determined by XTT assay. Greater growth inhibition was observed in the si-LY6K transfectants (BOY and KK47) than in the si-control transfectants. (C) Cell migration activity revealed by the wound healing assay. Greater inhibition of cell migration was observed in si-LY6K transfectant (BOY) than in the si-control transfectant. (D) Cell invasion activity by matrigel invasion assay. The number of cells invading through the membrane was significantly lower in the si-LY6K transfectant (BOY) than in the si-control transfectant.