Table 2. Highly gained loci in BC cell lines.
|
Location
|
Cell lines with gained loci
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Chromosome | Arm | Start | End | Size | No. of probes | P-value | No. | Name |
| Chr1 | p36.13 | 16 443 872 | 16 570 594 | 126 723 | 18 | 0.0052 | 4 | J82, T24, KK47, BOY |
| Chr1 | p36.11 | 26 486 288 | 26 582 083 | 95 796 | 15 | 0.0055 | 4 | T24, BOY, KK47, J82 |
| Chr5 | q35.3 | 179 048 014 | 179 182 725 | 134 712 | 18 | 0.0025 | 4 | BOY, KK47, T24, UMUC |
| Chr6 | p22.1 | 29 854 670 | 29 923 588 | 68 919 | 9 | 0.0075 | 4 | UMUC, BOY, KK47, J82 |
| Chr6 | p21.33-p21.32 | 32 450 499 | 32 450 899 | 401 | 1 | 0.0012 | 5 | KK47, UMUC, T24, BOY, J82 |
| Chr8 | q13.1 | 66 942 022 | 67 492 376 | 550 355 | 52 | 0.0024 | 4 | T24, BOY, UMUC, J82 |
| Chr8 | q23.3-q24.3 | 115 977 013 | 146 294 242 | 30 317 230 | 2404 | 0.0009 | 4 | UMUC, J82, KK47, BOY |
| Chr8 | q24.3 | 141 934 794 | 146 151 558 | 4 216 765 | 496 | 0.0019 | 5 | T24, UMUC, J82, BOY, KK47 |
| Chr9 | p13.3-p13.2 | 35 863 145 | 36 917 314 | 1054 170 | 105 | 0.0030 | 4 | J82, KK47, UMUC, T24 |
| Chr9 | q32 | 116 756 726 | 117 059 739 | 303 014 | 45 | 0.0052 | 4 | BOY, KK47, T24, J82 |
| Chr9 | q33.3-q34.3 | 129 659 306 | 140 696 609 | 11 037 304 | 1379 | 0.0074 | 4 | BOY, T24, J82, KK47 |
| Chr9 | q34.13 | 134 348 656 | 135 612 832 | 1 264 177 | 145 | 0.0069 | 5 | UMUC, BOY, T24, J82, KK47 |
| Chr11 | p13 | 33 673 844 | 33 768 828 | 94 985 | 13 | 0.0083 | 4 | KK47, J82, UMUC, BOY |
| Chr11 | q13.1 | 65 200 770 | 65 338 587 | 137 818 | 18 | 0.0011 | 5 | UMUC, BOY, J82, T24, KK47 |
| Chr11 | q13.2-q13.4 | 66 619 419 | 74 488 807 | 7 869 389 | 807 | 0.0012 | 5 | BOY, J82, T24, KK47, UMUC |
| Chr11 | q13.3-q14.1 | 70 270 969 | 78 189 879 | 7 918 911 | 847 | 0.0050 | 5 | BOY, J82, T24, UMUC, KK47 |
| Chr12 | q13.11-q13.2 | 46 756 675 | 56 434 303 | 9 677 629 | 1216 | 0.0013 | 4 | T24, UMUC, BOY, KK47 |
| Chr12 | q13.12 | 50 421 056 | 50 642 687 | 221 632 | 30 | 0.0078 | 5 | J82, UMUC, T24, KK47, BOY |
| Chr12 | q13.13 | 53 661 113 | 53 814 590 | 153 478 | 25 | 0.0087 | 5 | J82, UMUC, T24, KK47, BOY |
| Chr16 | p13.3 | 2 880 932 | 2 923 782 | 42 851 | 10 | 0.0051 | 5 | BOY, T24, J82, KK47, UMUC |
| Chr17 | q25.2 | 74 890 765 | 74 958 581 | 67 817 | 7 | 0.0088 | 4 | KK47, J82, T24, BOY |
| Chr20 | q11.21-q13.33 | 29 833 409 | 62 908 815 | 33 075 407 | 3101 | 0.0027 | 5 | BOY, UMUC, KK47, T24, J82 |
| ChrX | p22.2-p22.12 | 16 205 283 | 20 103 495 | 3 898 213 | 377 | 0.0070 | 4 | UMUC, J82, BOY, KK47 |
| ChrX | q11.1-q28 | 62 707 611 | 152 734 906 | 90 027 296 | 6184 | 0.0061 | 4 | KK47, UMUC, J82, BOY |
Abbreviations: BC=bladder cancer; Chr=chromosome.