Table 2. Mean EBV load (BamHIC copies) according to biological characteristics.
Characteristics | Mean EBV load (BamHIC copies per 100 ng GAPDH) | P-value |
---|---|---|
Age (years) | ||
<50 | 0.79 | 0.42 |
⩾50 | 7.84 | |
Tumour size (pT) | ||
<2 cm | 1.28 | 0.70 |
⩾2 cm | 10.60 | |
Nodal status (pN) | ||
N− | 1.40 | 0.34 |
N+ | 13 | |
Histological grade | ||
I | 0.32 | 0.006 |
II | 2.58 | |
III | 15.7 | |
ER | ||
Negative | 1.64 | 0.01 |
Positive | 20.58 | |
PR | ||
Negative | 1.83 | 0.20 |
Positive | 14.67 | |
UPA | ||
Low | 7.48 | 0.56 |
High | 1.12 | |
PAI-1 | ||
Low | 7.21 | 0.75 |
High | 1.93 | |
TK | ||
Low | 1.87 | 0.009 |
High | 17.95 | |
No HER2 amplification | 27.9 | 0.10 |
HER2 amplification | 1.9 |
Abbreviations: ER=oestrogen receptor; PAI-1=plasminogen activator inhibitor 1; PR=progesterone receptor; TK=thymidine kinase; UPA=urokinase plasminogen activator.