Table 4.

Western blot analysis of stress response and ubiquitination.

	CA1				CA3				DG				All
	AGE		CR		AGE		CR		AGE		CR		AGE		CR
Antigen	FC	P	FC	P	FC	P	FC	P	FC	P	FC	P	FC	P	FC	P
HSP90	1.21	NS	−1.95	0.089	1.23	NS	−1.64	0.098	1.21	NS	−1.76	0.066	1.22	NS	−1.77	0.001
HSP70	1.19	NS	−1.21	NS	−1.05	NS	−1.50	NS	−1.06	NS	−1.44	NS	1.03	NS	−1.35	NS
HSP40	1.15	NS	−1.15	NS	−1.04	NS	−1.42	NS	1.04	NS	−1.15	NS	1.05	NS	−1.22	NS
HSP27	27.03	0.003	1.15	NS	48.12	0.001	1.07	NS	12.66	0.036	−1.38	NS	29.28	0.001	1.05	NS
pUbi	1.24	NS	−1.13	NS	1.47	0.081	−1.01	NS	1.24	NS	1.04	NS	1.31	0.066	−1.03	NS
UBE2J	−1.04	NS	−1.55	NS	1.09	NS	−2.94	0.009	1.02	NS	−1.49	NS	1.02	NS	−1.83	0.005

The fold change for age represents comparisons between 8 mo-AL and 38 mo-AL rats. The fold change for CR represents comparisons between 38 mo-AL and 38 mo-CR rats. NS = not significant.