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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Biomaterials. 2011 Jan 8;32(10):2466–2478. doi: 10.1016/j.biomaterials.2010.12.024

Scheme 1.

Scheme 1

Synthetic procedures for the production of gelatin conjugated HA HGPs (gHGPs, A) and the gelatin-containing, doubly crosslinked networks (B). Gelatin was coupled to HA HGPs via the reductive amination reaction between the lysine amines on gelatin and the aldehyde groups on HA HGPs. The excess aldehyde groups were passivated by glycine. HA DXNs were prepared by entrapping gHGPs in a photocrosslinked HAGMA secondary matrix.