Table 1.

Effects of Thymine Glycol on DNA Unwinding by Various Helicases^a

Helicase	Organism	Directionality	Helicase Inhibition by TG
			Translocating Strand	Non-translocating Strand
FANCJ	Human	5’ to 3’	Yes	Yes
DinG	E. coli	5’ to 3’	No	No
DnaB	E. coli	5’ to 3’	No	No
UvrD	E. coli	3’ to 5’	No	No
BLM	Human	3’ to 5’	Yes	No
WRN	Human	3’ to 5’	Yes	No
RECQ1	Human	3’ to 5’	Yes	No

^aSee text and reference ⁸¹ for details.