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. Author manuscript; available in PMC: 2012 Feb 15.
Published in final edited form as: Respir Physiol Neurobiol. 2010 Dec 9;175(2):283–287. doi: 10.1016/j.resp.2010.12.003

Figure 3. Effect of pH and orexin on RTN neurons: group data.

Figure 3

A. Effect of bath pH on the steady-state discharge of 14 RTN neurons. There was a highly significant effect of pH on the discharge rate (P<0.001 by Kruskall-Wallis ANOVA on ranks). B. Increase in discharge rate elicited by four concentrations of orexin in the same 14 neurons recorded at pH 7.3 (up to 2 concentrations tested per neuron, 4 determinations for the 100, 300, and 500nM levels, 6 for the 200 nM concentration). There was a highly significant dose-effect relationship (P=0.002 by Kruskall-Wallis ANOVA on ranks). Asterisks denote statistically significant pair-wise comparisons. The pairs are identified by the end of the horizontal lines.