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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Chem Biol Interact. 2010 Dec 3;189(3):153–160. doi: 10.1016/j.cbi.2010.11.009

Figure 2.

Figure 2

Relationship between the estimated pKa values of OHPCBs and their inhibition of rSULT1A1. Log IC50 values for rSULT1A1 (with all cysteines in the thiol form) were determined previously [7]. The OHPCBs were divided into two groups, i.e., 4-OH-3,5-dichloro-PCBs (solid circles) and 4-OH-2(or 3)-chloro-PCBs (solid squares). The bivariate mean vectors (pKa and log IC50) in the two groups were significantly different from each other (Hotelling’s T-square test, p = 3.4 × 10−6). The chemical structures of the OHPCBs are shown in the order of their corresponding IC50 values.