Table 3.
Top-Ranking KEGG Pathways Associated with Colon Cancer Risk in the Women's Health Initiative Sample
Rank | KEGG Number | Pathway Name | No. Genes/No. eigenSNPs | p Value |
---|---|---|---|---|
1 | HSA00760 | Nicotinate and nicotinamide metabolism | 23/602 | 0.015 |
2 | HSA04350 | TGF-beta signaling | 89/2912 | 0.035 |
Top-ranking KEGG pathways that are associated with colon cancer risk at significance level α = 0.05. p values are calculated from Equation 6 based on 1000 permutations.