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. 2010 Jun 11;86(6):860–871. doi: 10.1016/j.ajhg.2010.04.014

Table 3.

Top-Ranking KEGG Pathways Associated with Colon Cancer Risk in the Women's Health Initiative Sample

Rank KEGG Number Pathway Name No. Genes/No. eigenSNPs p Value
1 HSA00760 Nicotinate and nicotinamide metabolism 23/602 0.015
2 HSA04350 TGF-beta signaling 89/2912 0.035

Top-ranking KEGG pathways that are associated with colon cancer risk at significance level α = 0.05. p values are calculated from Equation 6 based on 1000 permutations.